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Article

Polygenic influences on dyslipidemias.

Current opinion in lipidology - 1 Apr 2018

Dron Jacqueline S, Hegele Robert A

Abstract excerpt

PURPOSE OF REVIEW: Rare large-effect genetic variants underlie monogenic dyslipidemias, whereas common small-effect genetic variants - single nucleotide polymorphisms (SNPs) - have modest influences on lipid traits. Over the past decade, these small-effect SNPs have been shown to cumulatively exert consistent effects on lipid phenotypes under a polygenic framework, which is the focus of this review. RECENT...

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Identifiers

PMID: 29300201
DOI: 10.1097/MOL.0000000000000482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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