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Article

Resveratrol Inhibits Growth of Experimental Abdominal Aortic Aneurysm Associated With Upregulation of Angiotensin-Converting Enzyme 2.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2017

Moran Corey S, Biros Erik, Krishna Smriti M, Wang Yutang, Tikellis Chris, Morton Susan K, Moxon Joseph V, Cooper Mark E, Norman Paul E, Burrell Louise M, Thomas Merlin C, Golledge Jonathan

Abstract excerpt

OBJECTIVE: Recent evidence suggests an important role for angiotensin-converting enzyme 2 (ACE2) in limiting abdominal aortic aneurysm (AAA). This study examined the effect of ACE2 deficiency on AAA development and the efficacy of resveratrol to upregulate ACE2 in experimental AAA. APPROACH AND RESULTS: Ace2 deletion in apolipoprotein-deficient mice (ApoE-/-Ace2-/y ) resulted in increased aortic diameter and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28935757
DOI: 10.1161/ATVBAHA.117.310129

Genes

ACE2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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