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Article

The Paraoxonase Gene Cluster Protects Against Abdominal Aortic Aneurysm Formation.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2017

Yan Yun-Fei, Pei Jian-Fei, Zhang Yang, Zhang Ran, Wang Fang, Gao Peng, Zhang Zhu-Qin, Wang Ting-Ting, She Zhi-Gang, Chen Hou-Zao, Liu De-Pei

Abstract excerpt

OBJECTIVE: Abdominal aortic aneurysm (AAA) is a life-threatening vascular pathology, the pathogenesis of which is closely related to oxidative stress. However, an effective pharmaceutical treatment is lacking because the exact cause of AAA remains unknown. Here, we aimed at delineating the role of the paraoxonases (PONs) gene cluster (PC), which prevents atherosclerosis through the detoxification of oxidized...

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Identifiers

PMID: 27908891
DOI: 10.1161/ATVBAHA.116.308684

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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