Article
Contralateral breast cancers: Independent cancers or metastases?
International journal of cancer - 15 Jan 2018
Begg Colin B, Ostrovnaya Irina, Geyer Felipe C, Papanastasiou Anastasios D, Ng Charlotte K Y, Sakr Rita A, Bernstein Jonine L, Burke Kathleen A, King Tari A, Piscuoglio Salvatore, Mauguen Audrey, Orlow Irene, Weigelt Britta, Seshan Venkatraman E, Morrow Monica, Reis-Filho Jorge S
Abstract excerpt
A cancer in the contralateral breast in a woman with a previous or synchronous breast cancer is typically considered to be an independent primary tumor. Emerging evidence suggests that in a small subset of these cases the second tumor represents a metastasis. We sought to investigate the issue using massively parallel sequencing targeting 254 genes recurrently mutated in breast cancer. We examined the tumor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.