Article
Exome sequencing of contralateral breast cancer identifies metastatic disease.
Breast cancer research and treatment - 1 Jun 2015
Klevebring Daniel, Lindberg Johan, Rockberg Julia, Hilliges Camilla, Hall Per, Sandberg Maria, Czene Kamila
Abstract excerpt
Women with contralateral breast cancer (CBC) have significantly worse prognosis compared to women with unilateral cancer. A possible explanation of the poor prognosis of patients with CBC is that in a subset of patients, the second cancer is not a new primary tumor but a metastasis of the first cancer that has potentially obtained aggressive characteristics through selection of treatment. Exome and whole-genome...
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