Association between TLR-9 gene rs187084 polymorphism and knee osteoarthritis in a Chinese population.

doi:10.1042/BSR20170844

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Article

Association between TLR-9 gene rs187084 polymorphism and knee osteoarthritis in a Chinese population.

Bioscience reports - 31 Oct 2017

Zheng Mingfeng, Shi Shiyuan, Zheng Qi, Wang Yifan, Ying Xiaozhang, Jin Yanghui

Abstract excerpt

Osteoarthritis (OA) is a complex disease that is induced by many genetic risk variants and other factors. To examine the role of toll-like receptor 9 (TLR-9) in OA patients, we conducted a case-control study involving 215 knee OA (KOA) patients and 215 controls in a Chinese population. Genotyping with a custom-by-design 48-Plex single nucleotide polymorphism Scan™ Kit showed the TLR-9 gene rs187084 polymorphism...

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PMID: 28916728
DOI: 10.1042/BSR20170844
PMCID: PMC5643737

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