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Article

Association of X-linked TLR-7 gene polymorphism with the risk of knee osteoarthritis: a case-control study.

Scientific reports - 4 May 2022

Xi Xutao, Mehmood Arshad, Niu Pengyan, Yang Jinjie, Wang Yintian, Zhou Heyu, Han Xiaohui, Ma Lifen, Jin Shiying, Wu Yinxia

Abstract excerpt

Knee osteoarthritis (OA) is the most prevalent type of OA, and Toll-like receptor 7 (TLR7) may lead to the pathogenesis of OA. Recently, X-linked TLR7 polymorphism has been confirmed to be associated with arthritis. However, there is a lack of studies on TLR7 gene polymorphism associated with knee OA susceptibility. The current study aimed to determine whether TLR7 gene polymorphism is associated with the risk of...

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Identifiers

PMID: 35508687
DOI: 10.1038/s41598-022-11296-4
PMCID: PMC9068723

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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