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Article

TLR10 and NFKBIA contributed to the risk of hip osteoarthritis: systematic evaluation based on Han Chinese population.

Scientific reports - 6 Jul 2018

Tang Hongtao, Cheng Zhenzhen, Ma Wenlong, Liu Youwen, Tong Zhaofang, Sun Ruibo, Liu Hongliang

Abstract excerpt

Multiple lines of evidence have confirmed the importance of genetic factors for hip osteoarthritis (HOA). Our study aimed to investigate the associations of TLR10 and NFKBIA with respect to the HOA risk in Han Chinese individuals. A total of 1,043 HOA patients and 2,664 controls were recruited. Then, 23 tag single-nucleotide polymorphisms (SNPs) in the TLR10 and NFKBIA genes were selected for genotyping. Genetic...

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Source

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Identifiers

PMID: 29980729
DOI: 10.1038/s41598-018-28597-2
PMCID: PMC6035240

Genes

NFKBIA
TLR10

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