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Article

Genetic association between TNF-α G-308A and osteoarthritis in Asians: A case-control study and meta-analysis.

PloS one - 1 Jan 2021

Wang Chih-Chien, Huang Chih-Yun, Lee Meng-Chang, Tsai Dung-Jang, Wu Chia-Chun, Su Sui-Lung

Abstract excerpt

BACKGROUND: Osteoarthritis (OA) is an important health issue in elderly people. Many studies have suggested that genetic factors are important risk factors for OA, of which tumor necrosis factor-α (TNF-α) is one of the most examined genes. Moreover, several studies have investigated the relationship between TNF-α G-308A polymorphisms and OA risk, but consistent results have not been obtained. OBJECTIVE: This...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34735544
DOI: 10.1371/journal.pone.0259561
PMCID: PMC8568107

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