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Article

Promoter polymorphism (T-1486C) of TLR-9 gene is associated with knee osteoarthritis in a Turkish population.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Nov 2017

Balbaloglu Ozlem, Sabah Ozcan Seda, Korkmaz Murat, Yılmaz Neziha

Abstract excerpt

In this study, we aimed to determine whether TLR-9 T-1486C SNP was associated with susceptibility to OA in the Turkish population. The study group comprised 272 patients with Grade 2-3-4 knee OA according to the Kellgren-Lawrence scoring system and the control group was formed of 296 individuals with Grade 0-1. The TLR-9 genotype were assessed by real-time polymerase chain reaction. An analysis of TLR-9 promoter...

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Source

Identifiers

PMID: 28295589
DOI: 10.1002/jor.23559

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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