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Article

The Th1/Th17 balance dictates the fibrosis response in murine radiation-induced lung disease.

Scientific reports - 14 Sept 2017

Paun Alexandra, Bergeron Marie-Eve, Haston Christina K

Abstract excerpt

Radiotherapy can result in lung diseases pneumonitis or fibrosis dependent on patient susceptibility. Herein we used inbred and genetically altered mice to investigate whether the tissue adaptive immune response to radiation injury influences the development of radiation-induced lung disease. Six inbred mouse strains were exposed to 18 Gy whole thorax irradiation and upon respiratory distress strains prone to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28912510
DOI: 10.1038/s41598-017-11656-5
PMCID: PMC5599556

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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