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Article

Radiation-induced lung fibrosis in a tumor-bearing mouse model is associated with enhanced Type-2 immunity.

Journal of radiation research - 1 Mar 2016

Chen Jing, Wang Yacheng, Mei Zijie, Zhang Shimin, Yang Jie, Li Xin, Yao Ye, Xie Conghua

Abstract excerpt

Lung fibrosis may be associated with Type-2 polarized inflammation. Herein, we aim to investigate whether radiation can initiate a Type-2 immune response and contribute to the progression of pulmonary fibrosis in tumor-bearing animals. We developed a tumor-bearing mouse model with Lewis lung cancer to receive either radiation therapy alone or radiation combined with Th1 immunomodulator unmethylated...

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Identifiers

PMID: 26703457
DOI: 10.1093/jrr/rrv077
PMCID: PMC4795947

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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