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Modeling radiation-induced lung injury: lessons learned from whole thorax irradiation

25 Oct 2018

Abstract excerpt

Models of thoracic irradiation have been developed as clinicians and scientists have attempted to decipher the events that led up to the pulmonary toxicity seen in human subjects following radiation treatment. The most common model is that of whole thorax irradiation (WTI), applied in a single dose. Mice, particularly the C57BL/6J strain, has been frequently used in these investigations, and has greatly informed...

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PMID: 30359147
DOI: 10.1080/09553002.2018.1532619

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