Article
Combined Tlr2 and Tlr4 deficiency increases radiation-induced pulmonary fibrosis in mice.
International journal of radiation oncology, biology, physics - 15 Jul 2010
Paun Alexandra, Fox Jessica, Balloy Viviane, Chignard Michel, Qureshi Salman T, Haston Christina K
Abstract excerpt
PURPOSE: To determine whether Toll-like receptor 2 or 4 genotype alters the lung response to irradiation in C57BL/6 mice using a model developing a phenotype that resembles radiotherapy-induced fibrosis in both histological characteristics and onset post-treatment. METHODS AND MATERIALS: The pulm...
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