Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Significant genetic association of a functional TFPI variant with circulating fibrinogen levels and coronary artery disease.

Molecular genetics and genomics : MGG - 1 Feb 2018

Naji Duraid Hamid, Tan Chengcheng, Han Fabin, Zhao Yuanyuan, Wang Junhan, Wang Dan, Fa Jingjing, Li Sisi, Chen Shanshan, Chen Qiuyun, Xu Chengqi, Wang Qing K

Abstract excerpt

The tissue factor pathway inhibitor (TFPI) gene encodes a protease inhibitor with a critical role in regulation of blood coagulation. Some genomic variants in TFPI were previously associated with plasma TFPI levels, however, it remains to be further determined whether TFPI variants are associated with other coagulation factors. In this study, we carried out a large population-based study with 2313 study subjects...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Coagulation
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibrinogen

Share to Genetic Association Studies

Share to Lipoproteins

Share to Partial Thromboplastin Time

Share to Prothrombin Time

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 28894953
DOI: 10.1007/s00438-017-1365-6
PMCID: PMC5794607

Genes

TFPI
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Significant genetic association of a functional TFPI variant with circulating fibrinogen levels and coronary artery disease.PMID 28894953Read ↗

Genetic determinants of tissue factor pathway inhibitor plasma levels.Semantic proximity Read ↗

Association study to evaluate TFPI gene in CAD in Han Chinese.Semantic proximity Read ↗

Functional characterization of polymorphisms in the human TFPI gene.Semantic proximity Read ↗

Single nucleotide polymorphisms in an intergenic chromosome 2q region associated with tissue factor pathway inhibitor plasma levels and venous thromboembolism.Semantic proximity Read ↗

A new T-287C polymorphism in the 5' regulatory region of the tissue factor pathway inhibitor gene. Association study of the T-287C and C-399T polymorphisms with coronary artery disease and plasma TFPI levels.Semantic proximity Read ↗

Leveraging cell type specific regulatory regions to detect SNPs associated with tissue factor pathway inhibitor plasma levels.Semantic proximity Read ↗

Analysis of sequence variations in the promoter region of the human tissue factor pathway inhibitor 2 gene in apoplectic patients and blood donors.Semantic proximity Read ↗

Tumor expression, plasma levels and genetic polymorphisms of the coagulation inhibitor TFPI are associated with clinicopathological parameters and survival in breast cancer, in contrast to the coagulation initiator TF.Semantic proximity Read ↗

Androgen-dependent tissue factor pathway inhibitor regulating protein: a review of its peripheral actions and association with cardiometabolic diseases.Semantic proximity Read ↗

A locus on chromosome 2 influences levels of tissue factor pathway inhibitor: results from the GAIT study.Semantic proximity Read ↗

Interaction between a genetic variant of the platelet fibrinogen receptor and fibrinogen levels in determining the risk of cardiovascular events.Semantic proximity Read ↗

A Genome-wide Study of Common and Rare Genetic Variants Associated with Circulating Thrombin Activatable Fibrinolysis Inhibitor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.