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Article

Analysis of sequence variations in the promoter region of the human tissue factor pathway inhibitor 2 gene in apoplectic patients and blood donors.

Annals of hematology - 1 Jan 2006

Siegling Sabine, Thyzel Elmar, Glahn Joerg, Kleesiek Knut, Götting Christian

Abstract excerpt

Tissue factor pathway inhibitor 2 (TFPI-2) is a Kunitz-type serine protease inhibitor with homology to TFPI-1, an important regulator of the extrinsic pathway of blood coagulation. Recent studies have focused on TFPI-2 and its implications for atherosclerosis. The promoter region and the exons of the human TFPI-2 gene were screened for sequence variations in 41 apoplectic patients and 140 blood donors with no...

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Source

Identifiers

PMID: 16247609
DOI: 10.1007/s00277-005-0023-y

Genes

TFPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Analysis of sequence variations in the promoter region of the human tissue factor pathway inhibitor 2 gene in apoplectic patients and blood donors.PMID 16247609Read ↗

A locus on chromosome 2 influences levels of tissue factor pathway inhibitor: results from the GAIT study.Semantic proximity Read ↗

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Functional characterization of polymorphisms in the human TFPI gene.Semantic proximity Read ↗

Single nucleotide polymorphisms in an intergenic chromosome 2q region associated with tissue factor pathway inhibitor plasma levels and venous thromboembolism.Semantic proximity Read ↗

Identification of novel, functional genetic variants in the human matrix metalloproteinase-2 gene: role of Sp1 in allele-specific transcriptional regulation.Semantic proximity Read ↗

Genetic variation at the human tissue-type plasminogen activator (tPA) locus: haplotypes and analysis of association to plasma levels of tPA.Semantic proximity Read ↗

Polymorphisms in the tissue factor pathway inhibitor gene are not associated with ischaemic stroke.Semantic proximity Read ↗

Association of Asn221Ser mutation in tissue factor pathway inhibitor-beta with plasma total tissue factor pathway inhibitor level.Semantic proximity Read ↗

A common 4G allele in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene as a risk factor for pulmonary embolism and arterial thrombosis in hereditary protein S deficiency.Semantic proximity Read ↗

A new T-287C polymorphism in the 5' regulatory region of the tissue factor pathway inhibitor gene. Association study of the T-287C and C-399T polymorphisms with coronary artery disease and plasma TFPI levels.Semantic proximity Read ↗

Polymorphisms of the tissue factor pathway inhibitor gene are associated with venous thromboembolism in the antiphospholipid syndrome and carriers of factor V Leiden.Semantic proximity Read ↗

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