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Noninvasive Prenatal Genetic Screening of Cell-Free Fetal DNA for Early Prediction of β-Thalassemia Using Fiber Optic Nanogold-Linked Sorbent Assay.

ACS sensors - 23 Aug 2024

Ngo Loan Thi, Chaudhari Pallavi, Wang Wei-Kai, Tseng Yen-Ta, Kuo Pao-Lin, Huang Chun-Jen, Chiang Chang-Yue, Chau Lai-Kwan, Huang Tze-Ta

Abstract excerpt

β-Thalassemia is a prevalent type of severe inherited chronic anemia, primarily identified in developing countries. The identification of single nucleotide polymorphisms (SNPs) plays a vital role in the early diagnosis of genetic diseases. Here, we reported the development of an amplification-free fiber optic nanogold-linked sorbent assay method using a fiber optic particle plasmon resonance (FOPPR) biosensor for...

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PMID: 39088458
DOI: 10.1021/acssensors.4c01194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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