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Article

Detection of human genome mutations associated with pregnancy complications using 3-D microarray based on macroporous polymer monoliths.

Talanta - 15 Jan 2016

Glotov A S, Sinitsyna E S, Danilova M M, Vashukova E S, Walter J G, Stahl F, Baranov V S, Vlakh E G, Tennikova T B

Abstract excerpt

Analysis of variations in DNA structure using a low-density microarray technology for routine diagnostic in evidence-based medicine is still relevant. In this work the applicability of 3-D macroporous monolithic methacrylate-based platforms for detection of different pathogenic genomic substitutions was studied. The detection of nucleotide replacements in F5 (Leiden G/A, rs6025), MTHFR (C/T, rs1801133) and ITGB3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26592644
DOI: 10.1016/j.talanta.2015.09.066

Genes

MTHFR
SERPINE1
AGTR2
COMT
ITGB3
PON1
TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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