Article
HLA-DPB1 matching in unrelated hematopoietic stem cell transplantation program contributes to a higher incidence of disease relapse.
Human immunology - 1 Nov 2017
Burek Kamenaric Marija, Maskalan Marija, Grubic Zorana, Mikulic Mirta, Serventi Seiwerth Ranka, Durakovic Nadira, Vrhovac Radovan, Stingl Jankovic Katarina, Zunec Renata
Abstract excerpt
The impact of patient/donor matching for HLA-A, -B, -C, -DRB1 and -DQB1 genes in hematopoietic stem cell transplantation (HSCT) is well-recognized, but typing for additional genes, such as HLA-DPB1, is still controversial. Based on defined T-cell epitope (TCE) groups, all HLA-DPB1 mismatches can be classified as permissive or non-permissive. In this retrospective study we analysed 82 patient-matched unrelated...
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