Article
The importance of HLA-DPB1 in unrelated donor hematopoietic cell transplantation.
Blood - 15 Dec 2007
Shaw Bronwen E, Gooley Theodore A, Malkki Mari, Madrigal J Alejandro, Begovich Ann B, Horowitz Mary M, Gratwohl Alois, Ringdén Olle, Marsh Steven G E, Petersdorf Effie W
Abstract excerpt
Hematopoietic cell transplantation (HCT) from an HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 allele-matched unrelated donor is a well-recognized life-saving treatment modality for patients with hematologic disorders. The morbidity and mortality from clinically significant acute graft-versus-host disease (aGVHD) remains a limitation. The extent to which transplantation outcome may be improved with donor matching...
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