A T-cell epitope encoded by a subset of HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation.

doi:10.1182/blood-2003-04-1279

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Article

A T-cell epitope encoded by a subset of HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation.

Blood - 15 Feb 2004

Zino Elisabetta, Frumento Guido, Marktel Sarah, Sormani Maria Pia, Ficara Francesca, Di Terlizzi Simona, Parodi Anna Maria, Sergeant Ruhena, Martinetti Miryam, Bontadini Andrea, Bonifazi Francesca, Lisini Daniela, Mazzi Benedetta, Rossini Silvano, Servida Paolo, Ciceri Fabio, Bonini Chiara, Lanino Edoardo, Bandini Giuseppe, Locatelli Franco, Apperley Jane, Bacigalupo Andrea, Ferrara Giovanni Battista, Bordignon Claudio, Fleischhauer Katharina

Abstract excerpt

The importance of HLA-DPB1 matching for the outcome of allogeneic hematologic stem cell (HSC) transplantation is controversial. We have previously identified HLA-DPB1*0901 as a target of cytotoxic T cells mediating in vivo rejection of an HSC allograft. Here we show that HLA-DPB1*0901 encodes a T-cell epitope shared by a subset of DPB1 alleles that determines nonpermissive mismatches for HSC transplantation....

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PMID: 14576061
DOI: 10.1182/blood-2003-04-1279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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