Article
Investigation of the impact of HLA-DPB1 matching status in 10/10 HLA matched unrelated hematopoietic stem cell transplantation: results of a French single center study.
Human immunology - 1 Jul 2012
Touzeau Cyrille, Gagne Katia, Sébille Véronique, Herry Patricia, Chevallier Patrice, Folléa Gilles, Devys Anne, Moreau Philippe, Mohty Mohamad, Cesbron Gautier Anne
Abstract excerpt
The impact of HLA-DPB1 mismatches after unrelated hematopoietic stem cell transplantation (HSCT) remains controversial. We retrospectively analyzed the impact of permissive/non-permissive HLA-DPB1 mismatches on the outcome of 141 patients who underwent 10/10 HLA allelic-matched unrelated HSCT. Each pair was classified according to the 3 (TCE3) and 4-group (TCE4) algorithm based on DPB1 alleles immunogenicity....
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