Article
Ribavirin steady-state plasma level is a predictor of sustained virological response in hepatitis C-infected patients treated with direct-acting antivirals.
Alimentary pharmacology & therapeutics - 1 Nov 2017
van Tilborg M, Lieveld F I, Smolders E J, van Erpecum K J, de Kanter C T M M, Maan R, van der Valk M, Arends J E, Dofferhoff A S M, Blokzijl H, Bijmolen M, Drenth J P H, de Knegt R J, Burger D M
Abstract excerpt
BACKGROUND: In the era of highly effective direct-acting antivirals (DAAs) for treatment of patients with chronic hepatitis C virus (HCV) infection, ribavirin (RBV) is still considered beneficial in certain patients. AIM: To assess the association between RBV steady-state plasma levels and sustained virological response (SVR). METHODS: Consecutive HCV-infected patients treated with DAAs plus RBV from four Dutch...
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