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Article

Hepatitis C RNA assay differences in results: Potential implications for shortened therapy and determination of Sustained Virologic Response.

Scientific reports - 20 Oct 2016

Cloherty Gavin, Chevaliez Stephane, Sarrazin Christoph, Herman Christine, Holzmayer Vera, Dawson George, Maasoumy Benjamin, Vermehren Johannes, Wedemeyer Heiner, Feld Jordan J, Pawlotsky Jean-Michel

Abstract excerpt

Approval of Ledipasvir/Sofosbuvir for the treatment of chronic hepatitis C (HCV) includes the truncation of therapy from 12 to 8 weeks in treatment naïve, non-cirrhotic patients with baseline HCV RNA levels <6 million IU/mL (6.8 log10 IU/mL). The aim of this study was to evaluate this clinical cutoff with a different widely used commercially available HCV RNA test. Results from samples tested prospectively with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27762283
DOI: 10.1038/srep35410
PMCID: PMC5071881

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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