Article
High-Dose Ribavirin Enhances Early Virological Response in Hepatitis C Genotype 1-Infected Patients.
Therapeutic drug monitoring - 1 Dec 2015
Lindahl Karin, Hörnfeld Erika, Ståhle Lars, Carlsson Tony, Weiland Ola, Parke Åsa, Schvarcz Robert
Abstract excerpt
BACKGROUND: The aim of the study was to investigate whether patients with a previous nonresponse to standard of care treatment with ribavirin dosed according to body weight would respond to a high individualized dose of concentration-monitored ribavirin. METHODS: Previous nonresponders to standard of care treatment with peginterferon (peg-IFN) and ribavirin were included. Ribavirin was dosed aiming at a plasma...
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