Article
Influence of Ribavirin Serum Levels on Outcome of Antiviral Treatment and Anemia in Hepatitis C Virus Infection.
PloS one - 1 Jan 2016
Kuntzen Thomas, Kuhn Sereina, Kuntzen Daniela, Seifert Burkhardt, Müllhaupt Beat, Geier Andreas
Abstract excerpt
BACKGROUND: Ribavirin blood levels vary considerably between patients with standard weight-based dosing. Their impact on sustained virological response (SVR) with pegylated interferon and ribavirin is controversial, but has mostly been studied before the IL28b gene polymorphism as a possible confounder was discovered. METHODS: The impact of serum ribavirin trough levels at week 4, at the end of treatment and of...
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