Determining the lower limit of detection required for HCV viral load assay for test of cure following direct-acting antiviral-based treatment regimens: Evidence from a global data set.

doi:10.1111/jvh.13672

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Article

Determining the lower limit of detection required for HCV viral load assay for test of cure following direct-acting antiviral-based treatment regimens: Evidence from a global data set.

Journal of viral hepatitis - 1 Jun 2022

Morgan Jake R, Marsh Elizabeth, Savinkina Alexandra, Shilton Sonjelle, Shadaker Shaun, Tsertsvadze Tengiz, Kamkamidze George, Alkhazashvili Maia, Morgan Timothy, Belperio Pam, Backus Lisa, Doss Waheed, Esmat Gamal, Hassany Mohamed, Elsharkawy Aisha, Elakel Wafaa, Mehrez Mai, Foster Graham R, Wose Kinge Constance, Chew Kara W, Chasela Charles S, Sanne Ian M, Thanung Yin M, Loarec Anne, Aslam Khawar, Balkan Suna, Easterbrook Philippa J, Linas Benjamin P

Abstract excerpt

Achieving global elimination of hepatitis C virus requires a substantial scale-up of testing. Point-of-care HCV viral load assays are available as an alternative to laboratory-based assays to promote access in hard to reach or marginalized populations. The diagnostic performance and lower limit of detection are important attributes of these new assays for both diagnosis and test of cure. Therefore, our objective...

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Identifiers

PMID: 35278339
DOI: 10.1111/jvh.13672
PMCID: PMC9248016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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