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FOXO Transcriptional Factors and Long‐Term Living

1 Jan 2017

Abstract excerpt

Several pathologies such as neurodegeneration and cancer are associated with aging, which is affected by many genetic and environmental factors. Healthy aging conceives human longevity, possibly due to carrying the defensive genes. For instance, FOXO (forkhead box O) genes determine human longevity. FOXO transcription factors are involved in the regulation of longevity phenomenon via insulin and insulin-like...

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PMID: 28894507
DOI: 10.1155/2017/3494289

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