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Article

LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells.

Scientific reports - 31 Aug 2017

Lim So-Young, Macheleidt Iris, Dalvi Priya, Schäfer Stephan C, Kerick Martin, Ozretić Luka, Ortiz-Cuaran Sandra, George Julie, Merkelbach-Bruse Sabine, Wolf Jürgen, Timmermann Bernd, Thomas Roman K, Schweiger Michal R, Buettner Reinhard, Odenthal Margarete

Abstract excerpt

The epigenetic writer lysine-specific demethylase 1 (LSD1) is aberrantly upregulated in many cancer types and its overexpression correlates with poor survival and tumor progression. In this study, we analysed LSD1 function in non-small cell lung cancer adenocarcinomas. Expression profiling of 182 cases of lung adenocarcinoma proved a significant correlation of LSD1 overexpression with lung adenocarcinoma...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28860622
DOI: 10.1038/s41598-017-09554-x
PMCID: PMC5578970

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KRAS

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LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells.PMID 28860622Read ↗

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