Article

Carcinogenesis promotion in oral squamous cell carcinoma: KDM4A complex-mediated gene transcriptional suppression by LEF1

2023-03-14

Abstract excerpt

<title>Abstract</title> <p>Oral squamous cell carcinoma (OSCC) is the most prevalent cancer of the mouth, characterised by rapid progression and poor prognosis. Hence, there is an urgent need to develop predictive targets for early diagnosis, prognosis determination, and clinical therapy. Dysregulation of lymphoid enhancer-binding factor 1 (LEF1), an important transcription factor involved in the Wnt-β-catenin pa...

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Literature Corpus work: 73051bd0-3536-587d-ad4a-081a9a3b101c
DOI: 10.21203/rs.3.rs-2618088/v1

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