Article
Genetic Dissection of Trabecular Bone Structure with Mouse Intersubspecific Consomic Strains.
G3 (Bethesda, Md.) - 5 Oct 2017
Kataoka Taro, Tamura Masaru, Maeno Akiteru, Wakana Shigeharu, Shiroishi Toshihiko
Abstract excerpt
Trabecular bone structure has an important influence on bone strength, but little is known about its genetic regulation. To elucidate the genetic factor(s) regulating trabecular bone structure, we compared the trabecular bone structures of two genetically remote mouse strains, C57BL/6J and Japanese wild mouse-derived MSM/Ms. Phenotyping by X-ray micro-CT revealed that MSM/Ms has structurally more fragile...
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