Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Trps1 differentially modulates the bone mineral density between male and female mice and its polymorphism associates with BMD differently between women and men.

PloS one - 1 Jan 2014

Wang Lishi, Lu Wenli, Zhang Lei, Huang Yue, Scheib Rachel, Liu Xiaoyun, Myers Linda, Lu Lu, Farber Charles R, Liu Gaifen, Wang Cong-Yi, Deng Hongwen, Williams Robert W, Wang Yongjun, Gu Weikuan, Jiao Yan

Abstract excerpt

The objective of our study was to identify genetic factors that regulate bone mineral density (BMD) in mice using well defined recombinant inbred strains. For this purpose we chose the BXD recombinant inbred (RI) strains derived from progeny of the C57BL/6J (B6) and DBA/2J (D2) progenitor strains. We sampled both male and female mice (∼4 each) of 46 strains at 3 months-of-age, measured their BMD, and conducted...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Density
Share to Chromosomes, Human, Pair 15

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to GATA Transcription Factors

Share to Inbreeding

Share to Quantitative Trait Loci

Share to Repressor Proteins

Share to Sex Characteristics

Source

Open in PubMed Open full text

Identifiers

PMID: 24416236
DOI: 10.1371/journal.pone.0084485
PMCID: PMC3885592

Genes

TRPS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Trps1 differentially modulates the bone mineral density between male and female mice and its polymorphism associates with BMD differently between women and men.PMID 24416236Read ↗

Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density.Semantic proximity Read ↗

Genes influencing spinal bone mineral density in inbred F344, LEW, COP, and DA rats.Semantic proximity Read ↗

Mouse genome-wide association and systems genetics identifies Lhfp as a regulator of bone massSemantic proximity Read ↗

Deletion of Trps1 regulatory elements recapitulates postnatal hip joint abnormalities and growth retardation of Trichorhinophalangeal syndrome in mice.Semantic proximity Read ↗

Mouse Genome-Wide Association and Systems Genetics Identifies <i>Lhfp</i> as a Regulator of Bone MassSemantic proximity Read ↗

Congenic mice provide in vivo evidence for a genetic locus that modulates intrinsic transforming growth factor β1-mediated signaling and bone acquisition.Semantic proximity Read ↗

High-resolution genome screen for bone mineral density in heterogeneous stock rat.Semantic proximity Read ↗

Quantitative trait loci for bone mineral density and femoral morphology in an advanced intercross population of mice.Semantic proximity Read ↗

Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis.Semantic proximity Read ↗

Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture.Semantic proximity Read ↗

Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes.Semantic proximity Read ↗

Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.