Article

Multi-Scale Cortical Bone Traits Vary in Two Mouse Models of Genetic Diversity

2023-06-06

Abstract excerpt

Understanding the genetic basis of cortical bone traits can allow for the discovery of novel genes or biological pathways regulating bone health. Mice are the most widely used mammalian model for skeletal biology and allow for the quantification of traits that can’t easily be evaluated in humans, such as osteocyte lacunar morphology. The goal of our study was to investigate the effect of genetic diversity on multi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 825883d2-6bda-5285-83c4-78630215923c
DOI: 10.1101/2023.06.02.543484

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multi-Scale Cortical Bone Traits Vary in Two Mouse Models of Genetic DiversityDOI 10.1101/2023.06.02.543484Read

Genetic variation in bone growth patterns defines adult mouse bone fragility.Semantic proximity Read

A study of the influence of genetic variance and sex on the density and thickness of the calvarial bone in collaborative cross mice.Semantic proximity Read

Genetics of murine craniofacial morphology: diallel analysis of the eight founders of the Collaborative Cross.Semantic proximity Read

Quantitative trait loci for femoral size and shape in a genetically heterogeneous mouse population.Semantic proximity Read

Genetic variability in adult bone density among inbred strains of miceSemantic proximity Read

Facial shape and allometry quantitative trait locus intervals in the Diversity Outbred mouse are enriched for known skeletal and facial development genes.Semantic proximity Read

Quantitative trait loci modulate vertebral morphology and mechanical properties in a population of 18-month-old genetically heterogeneous miceSemantic proximity Read

High-throughput phenotyping and genetic linkage of cortical bone microstructure in the mouse.Semantic proximity Read

Use of a natural hybrid zone for genomewide association mapping of craniofacial traits in the house mouse.Semantic proximity Read

Using the Mus musculus hybrid zone to assess covariation and genetic architecture of limb bone lengths.Semantic proximity Read

Mapping of Craniofacial Traits in Outbred Mice Identifies Major Developmental Genes Involved in Shape Determination.Semantic proximity Read

Genome-wide association study in Collaborative Cross mice reveals a role for <i>Rhbdf2</i> in skeletal homeostasisSemantic proximity Read