Article
An application of competitive reporter monitored amplification (CMA) for rapid detection of single nucleotide polymorphisms (SNPs).
PloS one - 1 Jan 2017
Havlicek Juliane, Rivera-Milla Eric, Slickers Peter, Andres Sönke, Feuerriegel Silke, Niemann Stefan, Merker Matthias, Labugger Ines
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are essential parameters in molecular diagnostics and can be used for the early detection and clinical prognosis in various diseases. Available methods for SNP detection are still labor-intensive and require a complex laboratory infrastructure, which are not suitable for the usage in resource-limited settings. Thus, there is an urgent need for a simple, reliable and rapid...
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