Article
Rapid detection of multidrug-resistant tuberculosis based on allele-specific recombinase polymerase amplification and colorimetric detection.
PloS one - 1 Jan 2021
Singpanomchai Nuntita, Akeda Yukihiro, Tomono Kazunori, Tamaru Aki, Santanirand Pitak, Ratthawongjirakul Panan
Abstract excerpt
Multidrug-resistant tuberculosis (MDR-TB) poses a serious threat to TB control. Early diagnosis and proper treatment are essential factors to limit the spread of the disease. The existing molecular tests for MDR-TB usually require specific instruments, steady power supply, and routine maintenance, which might be obstacles for low-resource settings. This study aimed to develop allele-specific isothermal...
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