Article
Rapid Microarray-Based Detection of Rifampin, Isoniazid, and Fluoroquinolone Resistance in Mycobacterium tuberculosis by Use of a Single Cartridge.
Journal of clinical microbiology - 1 Feb 2018
Havlicek Juliane, Dachsel Beatrice, Slickers Peter, Andres Sönke, Beckert Patrick, Feuerriegel Silke, Niemann Stefan, Merker Matthias, Labugger Ines
Abstract excerpt
The rapid and robust identification of mutations in Mycobacterium tuberculosis complex (MTBC) strains mediating multidrug-resistant (MDR) and extensively drug-resistant (XDR) phenotypes is crucial to combating the MDR tuberculosis (TB) epidemic. Currently available molecular anti-TB drug susceptibility tests either are restricted to a single target or drug (i.e., the Xpert MTB/RIF test) or present a risk of...
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