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Article

Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels.

Scientific reports - 21 Aug 2017

Chae Soomin, Lee Hyun-Kyung, Kim Yoo-Kyung, Jung Sim Hyo, Ji Yoorim, Kim Chowon, Ismail Tayaba, Park Jeen-Woo, Kwon Oh-Shin, Kang Beom-Sik, Lee Dong-Seok, Bae Jong-Sup, Kim Sang-Hyun, Min Kyoung-Jin, Kyu Kwon Taeg, Park Mae-Ja, Han Jin-Kwan, Kwon Taejoon, Park Tae-Joo, Lee Hyun-Shik

Abstract excerpt

Peroxiredoxin1 (Prdx1) is an antioxidant enzyme belonging to the peroxiredoxin family of proteins. Prdx1 catalyzes the reduction of H2O2 and alkyl hydroperoxide and plays an important role in different biological processes. Prdx1 also participates in various age-related diseases and cancers. In this study, we investigated the role of Prdx1 in pronephros development during embryogenesis. Prdx1 knockdown markedly...

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Identifiers

PMID: 28827763
DOI: 10.1038/s41598-017-09262-6
PMCID: PMC5567039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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