Article
Peroxiredoxin5 Controls Vertebrate Ciliogenesis by Modulating Mitochondrial Reactive Oxygen Species.
Antioxidants & redox signaling - 10 May 2019
Ji Yurim, Chae Soomin, Lee Hyun-Kyung, Park Inji, Kim Chowon, Ismail Tayaba, Kim Youni, Park Jeen-Woo, Kwon Oh-Shin, Kang Beom-Sik, Lee Dong-Seok, Bae Jong-Sup, Kim Sang-Hyun, Moon Pyung-Gon, Baek Moon-Chang, Park Mae-Ja, Kil In Sup, Rhee Sue Goo, Kim Joon, Huh Yang Hoon, Shin Jong-Yeon, Min Kyoung-Jin, Kwon Taeg Kyu, Jang Dong Gil, Woo Hyun Ae, Kwon Taejoon, Park Tae Joo, Lee Hyun-Shik
Abstract excerpt
AIMS: Peroxiredoxin5 (Prdx5), a thioredoxin peroxidase, is an antioxidant enzyme that is widely studied for its antioxidant properties and protective roles in neurological and cardiovascular disorders. This study is aimed at investigating the functional significance of Prdx5 in mitochondria and at analyzing its roles in ciliogenesis during the process of vertebrate development. RESULTS: We found that several Prdx...
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