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Article

Spatial and Temporal Control of Senescence.

Trends in cell biology - 1 Nov 2017

Ito Yoko, Hoare Matthew, Narita Masashi

Abstract excerpt

Cellular senescence is an autonomous tumor suppressor mechanism leading to stable cell cycle arrest. Senescent cells are highly secretory, driving a range of different functions through the senescence-associated secretory phenotype (SASP). Recent findings have suggested that the composition of the SASP is dynamically and spatially regulated and that the changing composition of the SASP can determine the...

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Identifiers

PMID: 28822679
DOI: 10.1016/j.tcb.2017.07.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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