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Article

Cellular senescence and the tumour microenvironment.

Molecular oncology - 1 Sept 2022

Takasugi Masaki, Yoshida Yuya, Ohtani Naoko

Abstract excerpt

The senescence-associated secretory phenotype (SASP), where senescent cells produce a variety of secreted proteins including inflammatory cytokines, chemokines, matrix remodelling factors, growth factors and so on, plays pivotal but varying roles in the tumour microenvironment. The effects of SASP on the surrounding microenvironment depend on the cell type and process of cellular senescence induction, which is...

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Identifiers

PMID: 35674109
DOI: 10.1002/1878-0261.13268
PMCID: PMC9490140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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