Article

Molecular and genomic investigations of the role of MAP3K8 in IL-1β-induced response in respiratory epithelial cells

2012-01-01

Abstract excerpt

Mitogen Activated Protein 3 Kinase 8 (MAP3K8) is a member of the serine/threonine protein kinase family and has been demonstrated to be involved in the mitogen activated protein kinase (MAPK) pathway. The latter pathway plays an important role in many aspects of the immune mediated inflammatory response. Inhibition of MAP3K8 in primary human cell types decreases the production of TNF-α and other pro-inflammatory m...

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Literature Corpus work: bcf70683-cddb-5c7e-bc93-fc8bc652da55
DOI: 10.25560/9854

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