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Phosphatases in toll-like receptors signaling: the unfairly-forgotten

25 Jan 2021

Abstract excerpt

Over the past 2 decades, pattern recognition receptors (PRRs) have been shown to be on the front line of many illnesses such as autoimmune, inflammatory, and neurodegenerative diseases as well as allergies and cancer. Among PRRs, toll-like receptors (TLRs) are the most studied family. Dissecting TLRs signaling turned out to be advantageous to elaborate efficient treatments to cure autoimmune and chronic...

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PMID: 33494775
DOI: 10.1186/s12964-020-00693-9

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