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A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production

2023-05-27

Abstract excerpt

<h4>ABSTRACT</h4> Common respiratory diseases continue to represent a major public health problem, and much of the morbidity and mortality is due to airway inflammation and mucus production. Previous studies indicated a role for mitogen-activated protein kinase 14 (MAPK14) in this type of disease, but clinical trials are unsuccessful to date. Our previous work identified a related but distinct kinase known as MAP...

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Literature Corpus work
5e6caac7-43d4-5d11-8b2a-09fc913da8c2
DOI
10.1101/2023.05.26.542451
Open publication

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A potent MAPK13-14 inhibitor prevents airway inflammation and mucus productionDOI 10.1101/2023.05.26.542451
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