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Article

Mast cell plasticity and sphingosine-1-phosphate in immunity, inflammation and cancer.

Molecular immunology - 1 Jan 2015

Oskeritzian Carole A

Abstract excerpt

Mast cells (MC) are found in all vascularized tissues at homeostasis and, until recently, were viewed only as effector cells of allergic reactions via degranulation, the canonical process through which MC release mediators, including histamine and pre-formed proteases and cytokines such as TNF. Cross-linking of IgE bound to surface high affinity receptors for IgE (FcɛRI) by a specific antigen (Ag) triggers...

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Identifiers

PMID: 24766823
DOI: 10.1016/j.molimm.2014.03.018
PMCID: PMC4226394

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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