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Article

Impact of PNPLA3 and IFNL3 polymorphisms on hepatic steatosis in Asian patients with chronic hepatitis C.

PloS one - 1 Jan 2017

Huang Chao-Min, Chang Kuo-Chin, Hung Chao-Hung, Chiu King-Wah, Lu Sheng-Nan, Wang Jing-Houng, Chen Chien-Hung, Kee Kwong-Ming, Kuo Yuan-Hung, Tsai Ming-Chao, Tseng Po-Lin, Lin Ming-Tsung, Wu Cheng-Kun, Hu Tsung-Hui, Cho Chung-Lung, Yen Yi-Hao

Abstract excerpt

BACKGROUND AND AIMS: A recent meta-analysis revealed that the genotype PNPLA3 rs738409 GG is associated with a higher risk of hepatic steatosis (HS) in Caucasian patients with chronic hepatitis C (CHC). However, controversial results were found regarding Asian populations. Furthermore, previous studies have shown a negative association between interferon lambda 3 (IFNL3) rs12979860 CC and HS in Caucasian CHC...

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Topics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 28797039
DOI: 10.1371/journal.pone.0182204
PMCID: PMC5552214

Genes

IFNL3
PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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