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Article

Deciphering the genetic control of gene expression following Mycobacterium leprae antigen stimulation.

PLoS genetics - 1 Aug 2017

Manry Jérémy, Nédélec Yohann, Fava Vinicius M, Cobat Aurélie, Orlova Marianna, Thuc Nguyen Van, Thai Vu Hong, Laval Guillaume, Barreiro Luis B, Schurr Erwin

Abstract excerpt

Leprosy is a human infectious disease caused by Mycobacterium leprae. A strong host genetic contribution to leprosy susceptibility is well established. However, the modulation of the transcriptional response to infection and the mechanism(s) of disease control are poorly understood. To address this gap in knowledge of leprosy pathogenicity, we conducted a genome-wide search for expression quantitative trait loci...

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Identifiers

PMID: 28793313
DOI: 10.1371/journal.pgen.1006952
PMCID: PMC5565194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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