Article

A new paradigm for leprosy diagnosis based on host gene expression Insights from leprosy lesions transcriptomics

2021-07-30

Abstract excerpt

Transcriptional profiling is a powerful tool to investigate and detect human diseases. In this study, we used bulk RNA-sequencing (RNA-Seq) to compare the transcriptomes in skin lesions of leprosy patients or controls affected by other dermal conditions such as granuloma annulare, a confounder for paucibacillary leprosy. We identified five genes capable of accurately distinguishing multibacillary and paucibacillar...

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Literature Corpus work: 6a61c221-4466-59ad-979d-7e34149190f5
DOI: 10.1101/2021.07.30.454441

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