Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variants in calcium voltage-gated channel subunit Alpha1 C-gene (CACNA1C) are associated with sleep latency in infants.

PloS one - 1 Jan 2017

Kantojärvi Katri, Liuhanen Johanna, Saarenpää-Heikkilä Outi, Satomaa Anna-Liisa, Kylliäinen Anneli, Pölkki Pirjo, Jaatela Julia, Toivola Auli, Milani Lili, Himanen Sari-Leena, Porkka-Heiskanen Tarja, Paavonen Juulia, Paunio Tiina

Abstract excerpt

Genetic variants in CACNA1C (calcium voltage-gated channel subunit alpha1 C) are associated with bipolar disorder and schizophrenia where sleep disturbances are common. In an experimental model, Cacna1c has been found to modulate the electrophysiological architecture of sleep. There are strong genetic influences for consolidation of sleep in infancy, but only a few studies have thus far researched the genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Calcium Channels, L-Type

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Finland

Share to Polysomnography

Share to Schizophrenia

Share to Sleep Wake Disorders

Share to Surveys and Questionnaires

Source

Open in PubMed Open full text

Identifiers

PMID: 28792954
DOI: 10.1371/journal.pone.0180652
PMCID: PMC5549883

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variants in calcium voltage-gated channel subunit Alpha1 C-gene (CACNA1C) are associated with sleep latency in infants.PMID 28792954Read ↗

Disrupted Sleep-Dependent Neural Oscillations and Transcriptomic Changes in the <i>Cacna1g</i> Loss-of-Function Mouse Model Implicated in SchizophreniaSemantic proximity Read ↗

Replication of Genome-Wide Association Studies (GWAS) loci for sleep in the British G1219 cohort.Semantic proximity Read ↗

A genome-wide association study of sleep habits and insomnia.Semantic proximity Read ↗

Sleep Duration and Epilepsy Risk: Mendelian Randomization and Functional Validation of CACNA1A rs2228130-Related Inhibitory Synaptic Dysfunction.Semantic proximity Read ↗

Heritability and Genome-Wide Association Analyses of Sleep Duration in Children: The EAGLE Consortium.Semantic proximity Read ↗

Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.Semantic proximity Read ↗

Are some children genetically predisposed to poor sleep? A polygenic risk study in the general population.Semantic proximity Read ↗

Genetic and Environmental Factors Shape Infant Sleep Patterns: A Study of 18-Month-Old TwinsSemantic proximity Read ↗

Human genetics and sleep behavior.Semantic proximity Read ↗

An L-type calcium-channel gene mutated in incomplete X-linked congenital stationary night blindness.Semantic proximity Read ↗

Genome-wide association study of sleep duration in the Finnish population.Semantic proximity Read ↗

A single nucleotide polymorphism in the HOMER1 gene is associated with sleep latency and theta power in sleep electroencephalogram.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.