Article
Heritability and Genome-Wide Association Analyses of Sleep Duration in Children: The EAGLE Consortium.
Sleep - 1 Oct 2016
Marinelli Marcella, Pappa Irene, Bustamante Mariona, Bonilla Carolina, Suarez Anna, Tiesler Carla M, Vilor-Tejedor Natalia, Zafarmand Mohammad Hadi, Alvarez-Pedrerol Mar, Andersson Sture, Bakermans-Kranenburg Marian J, Estivill Xavier, Evans David M, Flexeder Claudia, Forns Joan, Gonzalez Juan R, Guxens Monica, Huss Anke, van IJzendoorn Marinus H, Jaddoe Vincent W V, Julvez Jordi, Lahti Jari, López-Vicente Mónica, Lopez-Espinosa Maria-Jose, Manz Judith, Mileva-Seitz Viara R, Perola Markus, Pesonen Anu-Katriina, Rivadeneira Fernando, Salo Perttu P, Shahand Shayan, Schulz Holger, Standl Marie, Thiering Elisabeth, Timpson Nicholas J, Torrent Maties, Uitterlinden André G, Smith George Davey, Estarlich Marisa, Heinrich Joachim, Räikkönen Katri, Vrijkotte Tanja G M, Tiemeier Henning, Sunyer Jordi
Abstract excerpt
STUDY OBJECTIVES: Low or excessive sleep duration has been associated with multiple outcomes, but the biology behind these associations remains elusive. Specifically, genetic studies in children are scarce. In this study, we aimed to: (1) estimate the proportion of genetic variance of sleep duration in children attributed to common single nucleotide polymorphisms (SNPs), (2) identify novel SNPs associated with...
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