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Article

Are some children genetically predisposed to poor sleep? A polygenic risk study in the general population.

Journal of child psychology and psychiatry, and allied disciplines - 1 May 2024

Kocevska Desana, Trajanoska Katerina, Mulder Rosa H, Koopman-Verhoeff M Elisabeth, Luik Annemarie I, Tiemeier Henning, van Someren Eus J W

Abstract excerpt

BACKGROUND: Twin studies show moderate heritability of sleep traits: 40% for insomnia symptoms and 46% for sleep duration. Genome-wide association studies (GWAS) have identified genetic variants involved in insomnia and sleep duration in adults, but it is unknown whether these variants affect sleep during early development. We assessed whether polygenic risk scores for insomnia (PRS-I) and sleep duration (PRS-SD)...

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Identifiers

PMID: 37936537
DOI: 10.1111/jcpp.13899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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